We study virus-host interactions with a focus on intrinsic cell defense mechanisms and their subversion by influenza viruses. Another area of interest in the lab is the biology of stress granules – cytoplasmic foci of messenger RNA-protein complexes that form in response to various types of stress.
News and announcements:
- 8 April 2020
PLoS Pearl minireview is out: Fine-tuning a blunt tool: Regulaton of viral host shutoff RNases. Daly et al., 2020.
Another collaborative work with Gaglia lab.
- 12 August 2019
Our lab receives infrastructure funding from CFI John R. Evans Leaders Fund (JELF)! As part of the $61 million investment in science projects across Canada, our award will fund state-of-the-art equipment that will boost research capacity in our lab and will be used by other Dal researchers as well!
- 22 April 2019
It’s great news: we received NSERC Discovery Grant that will support our research on stress granules for the next 5 years!!!
16 April 2019
Our collaborative Cell Reports paper with McCormick and Gaglia labs is out today!
The influenza A virus endoribonuclease PA-X usurps host mRNA processing machinery to limit host gene expression. Gaucherand et al., 2019.